Which phase follows inflammation and focuses on tissue proliferation and formation of new tissue?

Which phase follows inflammation and focuses on tissue proliferation and formation of new tissue?

• A. Maturation/Remodeling
• B. Inflammation
• C. Proliferation
• D. Hemostasis

Answer: (C)

After the inflammatory response, the wound enters the proliferative phase, where new tissue is built to replace the damaged area. In this phase, fibroblasts produce collagen and extracellular matrix, granulation tissue forms, new blood vessels grow (angiogenesis), and epithelial cells migrate to cover the wound. These activities drive tissue proliferation and the formation of fresh tissue that will later be strengthened during remodeling. Hemostasis occurs first to stop bleeding, and remodeling/maturation comes later to reorient and strengthen the tissue, so they don’t focus on creating new tissue in the same way.

After the inflammatory response, the wound enters the proliferative phase, where new tissue is built to replace the damaged area. In this phase, fibroblasts produce collagen and extracellular matrix, granulation tissue forms, new blood vessels grow (angiogenesis), and epithelial cells migrate to cover the wound. These activities drive tissue proliferation and the formation of fresh tissue that will later be strengthened during remodeling. Hemostasis occurs first to stop bleeding, and remodeling/maturation comes later to reorient and strengthen the tissue, so they don’t focus on creating new tissue in the same way.